Outcome of epilepsy surgery in focal cortical dysplasia

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Outcome of epilepsy surgery in focal cortical dysplasia.

OBJECTIVE To describe the outcome of surgery in patients with drug resistant epilepsy and a histopathological diagnosis of focal cortical dysplasia. METHODS AND SUBJECTS Analysis of histories and presurgical and follow up data was carried out in 53 patients with a histological diagnosis of focal cortical dysplasia. Their mean age was 24.0 years (range 5 to 46), and they included 14 children a...

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Focal Cortical Dysplasia and Epilepsy Surgery

Focal cortical dysplasia (FCD) is the most commonly encountered developmental malformation that causes refractory epilepsy. With advances in neuroimaging techniques, in particular MRI, recent studies have revealed a higher prevalence of FCD than previously estimated and have improved the preoperative identification and classification of these abnormalities. However, MRI frequently does not show...

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Multi-focal occurrence of cortical dysplasia in epilepsy patients.

This study describes the existence and the clinical and electrophysiological features of multi-focal cortical dysplasia in epilepsy patients. Five patients with intractable focal epilepsy are reported. All patients underwent invasive presurgical video-electroencephalography monitoring. Localization of dysplastic areas was based on high-resolution magnetic resonance scanning, surface and intracr...

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Surgical treatment of intractable epilepsy associated with focal cortical dysplasia.

Focal cortical dysplasias (FCDs) are congenital malformations of cortical development that are a frequent cause of refractory epilepsy in both children and adults. With advances in structural and functional neuroimaging, these lesions are increasingly being identified as a cause of intractable epilepsy in patients undergoing surgical management for intractable epilepsy. Comprehensive histologic...

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Surgical Treatment of Intractable Epilepsy Associated with Focal Cortical Dysplasia

Focal cortical dysplasias (FCDs), initially thought to be rare, are a common cause of drugrefractory epilepsy in both children and adults. Successful resection and subsequent characterization of FCDs was first described by Taylor et al. in 1971 from pathological specimens obtained in patients treated for intractable temporal lobe epilepsy (Tassi, et al.,2001; Becker, et al.,2002; Tassi, et al.,...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 2003

ISSN: 0022-3050

DOI: 10.1136/jnnp.74.2.183